Specialized Service Offering

Smoke Studies

Professional smoke studies for pharmaceutical and biotech applications. GMP-ready smoke testing services designed to visualize airflow patterns, validate contamination control, and ensure compliance with FDA, EU GMP, and global regulatory requirements.

Complete Smoke Studies Expertise

Smoke studies are critical testing procedures that visualize airflow patterns in cleanrooms and controlled environments. Sequence brings more than 22 years of hands-on experience supporting life science manufacturers with complex facility and process challenges. As an engineering consulting firm, Sequence focuses on ensuring that facilities, utilities, equipment, and manufacturing processes are designed, qualified, and tested to meet end user and regulatory requirements throughout the full project lifecycle.

This deep process and CQV expertise allows our team to integrate smoke study insights into broader contamination control and operational readiness strategies, helping clients achieve compliant, efficient, and reliable operations from initial design through routine production.

Where We Apply Our Expertise

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Laminar Airflow Testing
(BSC, Fume Hoods)

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Cleanroom Validation

❄️

HVAC System Verification

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Isolators

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Facility Design & Optimization

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Regulatory Compliant Execution

Precision Smoke Studies Airflow Visualization

Watch how our advanced smoke study techniques reveal critical airflow patterns in cleanroom environments

GMP-Ready Equipment & Personnel

Our certified technicians utilize state-of-the-art smoke generation equipment designed specifically for pharmaceutical and biotech cleanroom environments.

  • Trained & certified cleanroom personnel
  • Professional-grade smoke generation systems
  • High-resolution video documentation
  • Real-time analysis capabilities
  • Comprehensive regulatory compliance
Schedule a Consultation
Sequence technician performing airflow visualization

Turnkey Smoke Studies Solutions

From protocol development to final execution, we manage every aspect of your airflow visualization project.

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Custom High-Resolution Video Production

Professional documentation with detailed visual analysis to support protocol execution and regulatory submissions.

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Protocol Generation & Onsite Execution

Comprehensive protocol development tailored to your facility requirements, followed by expert onsite execution.

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GMP Ready Equipment

State-of-the-art smoke generation equipment operated by certified professionals with extensive cleanroom experience.

Cost-Effective & Timely Execution

Streamlined processes designed for reduced downtime and efficient scheduling to minimize impact on operations.

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Procedural Optimization

Leverage study results to optimize cleanroom procedures, material flows, and personnel movements for enhanced contamination control.

Complete Turnkey Solution

From initial consultation through final report delivery, we manage every aspect of your smoke study project.

Built on Compliance Excellence

Our smoke study services align with global regulatory requirements and industry best practices, ensuring your facility meets the highest standards.

International Society for Pharmaceutical Engineering standards

Guidance for Industry: Aseptic Processing

Annex 1 Compliance

Parenteral Drug Association Guidelines

Cleanroom & Controlled Environments

Current Good Manufacturing Practice

How We Work

Click to view our 5-step process

Initial Consultation

We assess your facility requirements, regulatory needs, and project objectives to develop a customized approach.

1
2

Protocol Development

Our team creates comprehensive, site-specific protocols that align with your SOPs and regulatory requirements.

Onsite Execution

Certified technicians perform smoke studies using professional-grade equipment with minimal disruption to operations.

3
4

Analysis & Reporting

Detailed analysis with high-resolution video documentation and actionable recommendations for optimization.

Ongoing Support

Post-project support to implement recommendations and ensure continued compliance and performance.

5

Ready to Validate Your Cleanroom Airflow?

Partner with the experts who understand both the science and compliance requirements of airflow visualization.

Get Started Today

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Tulip

No Code App Development for Manufacturing Operations

Tulip creates user-friendly and functional apps that improve the productivity of operations, without writing any code. Users can start from scratch or customize an App Template to fit their needs.

Sequence partners with Tulip for implementation and validation of the Tulip platform as well as creation, configuration and validation of Tulip Applications that are hosted on the platform. Our application builds include Electronic Batch Records, Weigh and Dispense, Digital SOPs for training (with embedded videos) and more.